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Check-in
25Nov2025Select date
Check-out
26Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507
Perfect
8.3
8.7
/10
4.5
4.2
/5

Art-Filled Accommodations

21C Museum Hotel Lexington occupies the historic Fayette National Bank Building. Rooms feature custom-designed furnishings, Malin+Goetz bath amenities, and original artwork. Options include City Queen beds, Deluxe King rooms, Corner Kings with two-exposure windows, and suites with separate living areas. The Two-bedroom Suite has heated bathroom tiles and a spa shower.

Lockbox Restaurant & Bar

Lockbox restaurant serves dishes using ingredients from Kentucky's limestone-rich soil, with menus that change frequently. The bar offers Kentucky bourbons, local beers, and creative cocktails. Private dining is available in the restored bank safe. Cocktail classes are offered through the Cocktail, Savings & Booze series.

Contemporary Art Museum

The hotel features over 7,000 square feet of exhibition space with rotating contemporary art exhibitions. Site-specific installations include 'Tomorrow's Weather' and 'Totally in Love' lampposts. Free guided tours are available daily. The property also includes a museum shop selling works from 60+ artists.

Downtown Lexington Location

Located at 167 West Main Street in downtown Lexington, 15 km from Blue Grass Airport. The hotel is 0.5 km from Kentucky Theatre, Hunt-Morgan House, Mary Todd Lincoln House, and Lexington Convention Center. The Distillery District with Mirror Twin Brewing and Ethereal Brewery is less than 1.6 km away.

Hotel Services & Amenities

Services include 24-hour valet parking ($30/night), same-day laundry, complimentary Wi-Fi, and pet-friendly rooms. The business center offers audiovisual capabilities. Event spaces accommodate 10-250 people. The hotel provides PATH water bottles as part of sustainability efforts and charges a $5 sustainability fee per stay.

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Choose the Room

From cosy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
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Check Dates & Room Rates

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Getting around

All Transportation Options at a Glance

City Centre
Lexington400 m
Airports
Blue Grass (LEX) 13.7 km

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
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Check-in
25Nov2025Select date
Check-out
26Nov2025Select date
Rooms and Guests2 Guests, 1 Room