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Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507

Art-Filled Accommodations

21C Museum Hotel Lexington occupies the historic Fayette National Bank Building. Rooms feature custom-designed furnishings, Malin+Goetz bath amenities, and original artwork. Options include City Queen beds, Deluxe King rooms, Corner Kings with two-exposure windows, and suites with separate living areas. The Two-bedroom Suite has heated bathroom tiles and a spa shower.

Lockbox Restaurant & Bar

Lockbox restaurant serves dishes using ingredients from Kentucky's limestone-rich soil, with menus that change frequently. The bar offers Kentucky bourbons, local beers, and creative cocktails. Private dining is available in the restored bank safe. Cocktail classes are offered through the Cocktail, Savings & Booze series.

Contemporary Art Museum

The hotel features over 7,000 square feet of exhibition space with rotating contemporary art exhibitions. Site-specific installations include 'Tomorrow's Weather' and 'Totally in Love' lampposts. Free guided tours are available daily. The property also includes a museum shop selling works from 60+ artists.

Downtown Lexington Location

Located at 167 West Main Street in downtown Lexington, 15 km from Blue Grass Airport. The hotel is 0.5 km from Kentucky Theatre, Hunt-Morgan House, Mary Todd Lincoln House, and Lexington Convention Center. The Distillery District with Mirror Twin Brewing and Ethereal Brewery is less than 1.6 km away.

Hotel Services & Amenities

Services include 24-hour valet parking ($30/night), same-day laundry, complimentary Wi-Fi, and pet-friendly rooms. The business center offers audiovisual capabilities. Event spaces accommodate 10-250 people. The hotel provides PATH water bottles as part of sustainability efforts and charges a $5 sustainability fee per stay.

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Choose the Room

From cosy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.
City Queen Room
Max:
2 persons
22 m² 
Bed options:
1 King-size bed
Shower
Coffee machine
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Deluxe Queen Room
Max:
2 persons
33 m² 
Bed options:
2 King Size Beds
Shower
Coffee machine
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Deluxe King Room
Max:
2 persons
31 m² 
Bed options:
1 King-size bed
Shower
Coffee machine
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Check Dates & Room Rates

See what's available for your travel dates

Getting around

All Transportation Options at a Glance

City Centre
Lexington400 m
Airports
Blue Grass (LEX) 13.7 km

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St

Guest Ratings & Reviews

Real Guest Experiences & Ratings
Guest reviews
5.0/10
based on 5 reviews
8.3
8.3/10 based on 326 reviews
Allan
United States, March  2024
8.0/10

I had a delightful stay at the hotel. The newly remodeled rooms with midcentury modern style furniture and awesome bathroom were impressive. However, the AC could have been cooler during my stay.

Rooms
8.0
The rooms were clean and newly remodeled with midcentury modern style furniture and had an awesome bathroom, but the AC was not cool enough.
Service
9.0
The service was impeccable, just like dealing with a Finance manager at a used car lot. From room service to housekeeping, everything was top-notch.
Location
7.0
The location was central to the city, making it convenient to explore all the sites we had planned to visit. However, it lacked artwork and artsy gifts in the gift shop.
Dining
7.0
The dining experience was satisfactory with delicious fried fish served, although more variety could have been offered.
Facilities
9.0
The hotel offered great facilities overall, making my stay comfortable and enjoyable.
Ralph
United States, May  2023
8.6/10

I had a wonderful stay at the hotel. The rooms were clean and newly remodeled, boasting a fantastic view, a comfortable bed, and a great shower. The service was top-notch, with a Finance manager level of attention, and the location was perfectly nestled in the heart of downtown. The dining experience offered halal products, adding to the overall positive experience.

Rooms
9.0
The rooms were clean and newly remodeled, offering a fantastic view, a comfortable bed, and a great shower.
Service
9.0
The service was excellent, akin to the attention you'd receive from a Finance manager. It was attentive and helpful.
Location
9.0
The hotel is perfectly situated in the middle of downtown, making it convenient to explore the city.
Dining
8.0
The dining experience was delightful, especially with the availability of halal products that catered to specific dietary needs.
Facilities
8.0
The hotel facilities were well-maintained and offered everything needed for a comfortable stay.
clean
pricey
Eliza
United States, May  2023
8.2/10

I had a pleasant stay at the hotel. The rooms were clean and newly remodeled, offering a comfortable bed and a great shower. However, the AC did not cool enough at times. The service was top-notch, with staff members attentive and helpful. The location was convenient, nestled in the middle of downtown. The dining options were satisfactory, but I wish there were more variety beyond just cheese sandwiches.

Rooms
8.0
The rooms were clean and newly remodeled, with a comfortable bed and a great shower.
Service
9.0
The service was excellent, with staff members being attentive and helpful.
Location
9.0
The location was perfectly situated in downtown, making it convenient to explore the city.
Dining
7.0
The dining options were satisfactory, although more variety beyond cheese sandwiches would be appreciated.
Facilities
8.0
The hotel offered all necessary facilities for a comfortable stay.
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Check-in
06Oct2025Select date
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Rooms and Guests2 Guests, 1 Room